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HealthValue
Hyperactive B lymphocytes :
B cell life span and receptors
Early B cell precursor
Pre B cell
Primary Mature B cell
Mature B cell
B cell membranes bear very many receptors. We have only highlighted those concerned by our topic. CD 20 is present neither at a very early stage, nor at a very mature stage. TACI, BCMA and BAFF-R appear later than CD 20, and persist into mature B cells.
- Pathways
- Diseases
- Lifespan and receptors
- Therapies
MONOCLONALS
abatacept
abciximab
adalimumab
alefacept
alemtuzumab
anti KDR
atacicept
basiliximab
belatacept
belimumab
bevacizumab
BR3-Fc
CDP 791
certolizumab
cetuximab
dacluzimab
denosumab
eculizumab
efalizumab
etanercept
IMC 1121
infliximab
ipilimumab
lumiliximab
Mab 806
mapatumumab
matuzumab
natalizumab
nimotuzumab
ocrelizumab
ofatumumab
omalizumab
palivizumab
panitumumab
pertuzumab
ranibizumab
rituximab
ticilimumab
trastuzumab
VEGF Trap
zalutumumab
ABOUT MONOCLONALS
what is a monoclonal
chains & fragments
therapeutic fields
what are CDs
types of monoclonals
fusion proteins
cells to build monoclonals
making monoclonals
IgG1/IgG2 differences
F(ab) fragments
Fc fragment
Fc structure
Fc e receptors
DISEASES
B lymphocyte hyperactivity
bird flu
cancer
diabetes
human growth hormone diseases
lysosomal diseases
mitochondrial diseases
multiple sclerosis
myelodysplastic sd
myopathies
osteoporosis
paroxysmal nocturnal hemoglobinuria
psoriasis
rheumatoid arthritis
BioTherapies
antisense
cell therapy
exon skipping
gene therapy
hemopoietic prog.
monoclonals
protein kinases
recombinant prot.
stem cells
Cells/organelles
B lymphocytes
cell cycle
cells
chromosomes
DNA repair
exons
hemopoietic prog.
introns
lysosomes
mb. receptors
membrane CDs
mitochondria
proteasomes
stem cells
Pathways
Adams
AKT
amino acids
APRIL
BLys
BRCA
complement
cancer pathways
cdk
c-Met
DPP IV
EGF
EGFRvIII
GPCR
G proteins
HGF
ILGF
kinome
Kras
mannose P
MET
mTOR
NFKB
nucleotides
protein kinases
proteins
Ras
RET
sheddases
sunitinib/sorafenib
TACI
TNF
VEGF
Wnt