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BLOCKING THE COMPLEMENT PATHWAY
with a Monoclonal Antibody
By blocking C5, and hence stopping the cascade that leads to C9 drilling a hole in the red cell, ECULIZUMAB,
a humanized anti C5 monoclonal antibody,  considerably decreases hemolysis in patients with PNH Paroxysmal
Nocturnal
Hemoglobinuria
whose red cells lack a surface protein that protects them from the action of "Complement".
Complement is a complex system of proteins that protects us against infection and abnormal cell proliferation.
HealthValue
Take a look at the red cell
during PNH ?, or after eating the
contaminated vegetables: click here
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BREAKING NEWS May 28 2011: Eculizumab life saving in EHEC* (shiga toxin E. coli toxi-infection) cucumber/salad/tomatoes alimentay infection. See the article in NEJM
FOR ALL OTHER INFO ON ENVIRONMENTAL DISEASES, RUSH TO OUR SPECIALIZED PAGES Click here
* or STEC-HUS : shiga toxin producing Eschericia coli Hemolytic Uremic syndrome