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Human Kinome
More than 700 genes control thousands of pathways in charge of the very life of each cell : the KINASE pathways. Kinases are enzymes that add phosphate ("phosphorylate") to protéins, and thus activate them and trigger a cascade of reactions.
Among these pathways 2 are very well known, and addressed by medicines
- the VEGF pathway (vascular endothelial growth factor)
- the EGF pathway (epidermal growth factor)
download from Science Magazine the fabulous poster on Human Kinome
VEGF
EGF
VEGFR
EGFR
protéines kinases
CANCEROGENESE
Many other Protein kinases exist. Their  inhibitors play or could play a therapeutic role, in cancers, transplantation, inflammatory and neuro-degenerative diseases
Go see the other protein kinases
Protein Kinases
Carcinogenesis
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